Description
transglutaminase 1 [Source:HGNC Symbol;Acc:HGNC:11777]
Gene Synonyms
ICR2, LI, LI1, TGASE, TGK
Location
Chromosome 14: 24,249,114-24,264,432 reverse strand.
GRCh38:CM000676.2
View alleles of this gene on alternative sequences
About this gene
This gene has 9 transcripts (splice variants), 1 gene allele, 461 orthologues, 9 paralogues and is associated with 6 phenotypes.
Transcripts
| Name | Transcript ID | bp | Protein | Translation ID | Biotype | CCDS | UniProt Match | RefSeq Match | Flags |
|---|---|---|---|---|---|---|---|---|---|
| TGM1-201 | ENST00000206765.11 | 2744 | 817aa | ENSP00000206765.6 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | CCDS9622 | P22735-1 | NM_000359.3 | <p>TSL 1: A transcript where all splice junctions are supported by at least one non-suspect mRNA.</p><p>The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users, based on the type and quality of the alignments used to annotate the transcript.</p>TSL:1, The GENCODE set is the gene set for human and mouse. <a href="/Help/Glossary?id=500" class="popup">GENCODE Basic</a> is a subset of representative transcripts (splice variants).GENCODE basic, <p>APPRIS P1: Transcript(s) expected to code for the main functional isoform based solely on the core modules in the APPRIS.</p><p>APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods to identify the most functionally important transcript(s) of a gene.</p>APPRIS P1, The Matched Annotation from NCBI and EMBL-EBI is a collaboration between Ensembl/GENCODE and RefSeq. The MANE Select is a default transcript per human gene that is representative of biology, well-supported, expressed and highly-conserved. This transcript set matches GRCh38 and is 100% identical between RefSeq and Ensembl/GENCODE for 5' UTR, CDS, splicing and 3'UTR.MANE Select v0.91, |
| TGM1-202 | ENST00000544573.5 | 1581 | 375aa | ENSP00000439446.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | - | P22735-2 | - | <p>TSL 2: A transcript where the best supporting mRNA is flagged as suspect or the support is from multiple ESTs</p><p>The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users, based on the type and quality of the alignments used to annotate the transcript.</p>TSL:2, The GENCODE set is the gene set for human and mouse. <a href="/Help/Glossary?id=500" class="popup">GENCODE Basic</a> is a subset of representative transcripts (splice variants).GENCODE basic, |
| TGM1-204 | ENST00000559136.1 | 898 | 209aa | ENSP00000453337.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | - | H0YLT9 | - | 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete, <p>TSL 5: A transcript where no single transcript supports the model structure.</p><p>The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users, based on the type and quality of the alignments used to annotate the transcript.</p>TSL:5, |
| TGM1-206 | ENST00000560226.1 | 580 | 42aa | ENSP00000454070.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | - | H0YNM4 | - | 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete, <p>TSL 2: A transcript where the best supporting mRNA is flagged as suspect or the support is from multiple ESTs</p><p>The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users, based on the type and quality of the alignments used to annotate the transcript.</p>TSL:2, |
| TGM1-208 | ENST00000560478.1 | 562 | 50aa | ENSP00000453234.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | - | H0YLJ6 | - | 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete, <p>TSL 4: A transcript where the best supporting EST is flagged as suspect</p><p>The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users, based on the type and quality of the alignments used to annotate the transcript.</p>TSL:4, |
| TGM1-203 | ENST00000558074.1 | 555 | 135aa | ENSP00000453840.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | - | H0YN27 | - | 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete, <p>TSL 5: A transcript where no single transcript supports the model structure.</p><p>The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users, based on the type and quality of the alignments used to annotate the transcript.</p>TSL:5, |
| TGM1-207 | ENST00000560443.1 | 527 | 64aa | ENSP00000452822.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | - | H0YKI6 | - | 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete, <p>TSL 4: A transcript where the best supporting EST is flagged as suspect</p><p>The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users, based on the type and quality of the alignments used to annotate the transcript.</p>TSL:4, |
| TGM1-209 | ENST00000561067.1 | 469 | 9aa | ENSP00000452690.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | - | A0A0G2JL93 | - | 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete, <p>TSL 4: A transcript where the best supporting EST is flagged as suspect</p><p>The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users, based on the type and quality of the alignments used to annotate the transcript.</p>TSL:4, |
| TGM1-205 | ENST00000559669.1 | 412 | 128aa | ENSP00000453701.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | - | H0YMQ8 | - | 5' truncation in transcript evidence prevents annotation of the start of the CDS.CDS 5' incomplete, <p>TSL 3: A transcript where the only support is from a single EST</p><p>The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users, based on the type and quality of the alignments used to annotate the transcript.</p>TSL:3, |
