Description
serpin family B member 8 [Source:HGNC Symbol;Acc:HGNC:8952]
Gene Synonyms
CAP2, PI8
Location
Chromosome 18: 63,970,029-64,019,779 forward strand.
GRCh38:CM000680.2
About this gene
This gene has 9 transcripts (splice variants), 601 orthologues, 36 paralogues and is associated with 2 phenotypes.
Transcripts
| Name | Transcript ID | bp | Protein | Translation ID | Biotype | CCDS | UniProt Match | RefSeq Match | Flags |
|---|---|---|---|---|---|---|---|---|---|
| SERPINB8-202 | ENST00000353706.6 | 3387 | 374aa | ENSP00000331368.3 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | CCDS11991 | P50452-1 | - | <p>TSL 5: A transcript where no single transcript supports the model structure.</p><p>The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users, based on the type and quality of the alignments used to annotate the transcript.</p>TSL:5, The GENCODE set is the gene set for human and mouse. <a href="/Help/Glossary?id=500" class="popup">GENCODE Basic</a> is a subset of representative transcripts (splice variants).GENCODE basic, <p>APPRIS P1: Transcript(s) expected to code for the main functional isoform based solely on the core modules in the APPRIS.</p><p>APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods to identify the most functionally important transcript(s) of a gene.</p>APPRIS P1, |
| SERPINB8-203 | ENST00000397985.7 | 3321 | 374aa | ENSP00000381072.2 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | CCDS11991 | P50452-1 | NM_002640.4 | <p>TSL 1: A transcript where all splice junctions are supported by at least one non-suspect mRNA.</p><p>The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users, based on the type and quality of the alignments used to annotate the transcript.</p>TSL:1, The GENCODE set is the gene set for human and mouse. <a href="/Help/Glossary?id=500" class="popup">GENCODE Basic</a> is a subset of representative transcripts (splice variants).GENCODE basic, <p>APPRIS P1: Transcript(s) expected to code for the main functional isoform based solely on the core modules in the APPRIS.</p><p>APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods to identify the most functionally important transcript(s) of a gene.</p>APPRIS P1, The Matched Annotation from NCBI and EMBL-EBI is a collaboration between Ensembl/GENCODE and RefSeq. The MANE Select is a default transcript per human gene that is representative of biology, well-supported, expressed and highly-conserved. This transcript set matches GRCh38 and is 100% identical between RefSeq and Ensembl/GENCODE for 5' UTR, CDS, splicing and 3'UTR.MANE Select v0.91, |
| SERPINB8-208 | ENST00000542677.5 | 3192 | 192aa | ENSP00000438328.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | CCDS62460 | P50452-3 | - | <p>TSL 2: A transcript where the best supporting mRNA is flagged as suspect or the support is from multiple ESTs</p><p>The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users, based on the type and quality of the alignments used to annotate the transcript.</p>TSL:2, The GENCODE set is the gene set for human and mouse. <a href="/Help/Glossary?id=500" class="popup">GENCODE Basic</a> is a subset of representative transcripts (splice variants).GENCODE basic, |
| SERPINB8-209 | ENST00000636430.1 | 1719 | 259aa | ENSP00000489949.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | CCDS86678 | A0A1B0GU38 | - | <p>TSL 5: A transcript where no single transcript supports the model structure.</p><p>The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users, based on the type and quality of the alignments used to annotate the transcript.</p>TSL:5, The GENCODE set is the gene set for human and mouse. <a href="/Help/Glossary?id=500" class="popup">GENCODE Basic</a> is a subset of representative transcripts (splice variants).GENCODE basic, |
| SERPINB8-204 | ENST00000397988.7 | 1178 | 242aa | ENSP00000381075.3 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | CCDS42442 | P50452-2 | - | <p>TSL 1: A transcript where all splice junctions are supported by at least one non-suspect mRNA.</p><p>The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users, based on the type and quality of the alignments used to annotate the transcript.</p>TSL:1, The GENCODE set is the gene set for human and mouse. <a href="/Help/Glossary?id=500" class="popup">GENCODE Basic</a> is a subset of representative transcripts (splice variants).GENCODE basic, |
| SERPINB8-201 | ENST00000295211.5 | 979 | 189aa | ENSP00000295211.5 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | - | H7BXK7 | - | 5' truncation in transcript evidence prevents annotation of the start of the CDS.CDS 5' incomplete, <p>TSL 3: A transcript where the only support is from a single EST</p><p>The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users, based on the type and quality of the alignments used to annotate the transcript.</p>TSL:3, |
| SERPINB8-207 | ENST00000493661.2 | 919 | 43aa | ENSP00000478199.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | - | A0A087WTX6 | - | 5' truncation in transcript evidence prevents annotation of the start of the CDS.CDS 5' incomplete, <p>TSL 3: A transcript where the only support is from a single EST</p><p>The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users, based on the type and quality of the alignments used to annotate the transcript.</p>TSL:3, |
| SERPINB8-206 | ENST00000448851.5 | 580 | 124aa | ENSP00000414580.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | - | C9JTJ8 | - | 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete, <p>TSL 4: A transcript where the best supporting EST is flagged as suspect</p><p>The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users, based on the type and quality of the alignments used to annotate the transcript.</p>TSL:4, |
| SERPINB8-205 | ENST00000441827.5 | 564 | 164aa | ENSP00000393456.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | - | C9JVA8 | - | 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete, <p>TSL 4: A transcript where the best supporting EST is flagged as suspect</p><p>The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users, based on the type and quality of the alignments used to annotate the transcript.</p>TSL:4, |
