Description
nuclear receptor coactivator 1 [Source:MGI Symbol;Acc:MGI:1276523]
Gene Synonyms
KAT13A, SRC-1, SRC-a/NCoA-1, SRC1, bHLHe74, steroid receptor coactivator-1
Location
Chromosome 12: 4,247,362-4,477,182 reverse strand.
GRCm38:CM001005.2
About this gene
This gene has 9 transcripts (splice variants), 289 orthologues, 2 paralogues and is associated with 49 phenotypes.
Transcripts
| Name | Transcript ID | bp | Protein | Translation ID | Biotype | CCDS | UniProt Match | Flags |
|---|---|---|---|---|---|---|---|---|
| Ncoa1-201 | ENSMUST00000085814.4 | 7329 | 1405aa | ENSMUSP00000082971.3 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | CCDS25789 | P70365 | <p>TSL 1: A transcript where all splice junctions are supported by at least one non-suspect mRNA.</p><p>The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users, based on the type and quality of the alignments used to annotate the transcript.</p>TSL:1, The GENCODE set is the gene set for human and mouse. <a href="/Help/Glossary?id=500" class="popup">GENCODE Basic</a> is a subset of representative transcripts (splice variants).GENCODE basic, <p>APPRIS P2: Where the APPRIS core modules are unable to choose a clear principal variant (approximately 25% of human protein coding genes), the database chooses two or more of the CDS variants as "candidates" to be the principal variant.</p><p>APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods to identify the most functionally important transcript(s) of a gene.</p>APPRIS P2, |
| Ncoa1-209 | ENSMUST00000220434.1 | 4756 | 1447aa | ENSMUSP00000151358.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | - | P70365 | <p>TSL 1: A transcript where all splice junctions are supported by at least one non-suspect mRNA.</p><p>The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users, based on the type and quality of the alignments used to annotate the transcript.</p>TSL:1, The GENCODE set is the gene set for human and mouse. <a href="/Help/Glossary?id=500" class="popup">GENCODE Basic</a> is a subset of representative transcripts (splice variants).GENCODE basic, <p>APPRIS ALT2: For genes in which the APPRIS core modules are unable to choose a clear principal isoform, the ALT1 is the candidate transcript(s) models that appear to be conserved in fewer than three tested species.</p><p>APPRIS is a system to annotate alternatively spliced transcripts based on a range of computational methods to identify the most functionally important transcript(s) of a gene.</p>APPRIS ALT2, |
| Ncoa1-202 | ENSMUST00000217674.1 | 2822 | 922aa | ENSMUSP00000151610.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | - | A0A1W2P7C1 | 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete, <p>TSL 5: A transcript where no single transcript supports the model structure.</p><p>The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users, based on the type and quality of the alignments used to annotate the transcript.</p>TSL:5, |
| Ncoa1-205 | ENSMUST00000218191.1 | 2069 | 430aa | ENSMUSP00000151744.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | - | A0A1W2P7S6 | 5' truncation in transcript evidence prevents annotation of the start of the CDS.CDS 5' incomplete, <p>TSL 1: A transcript where all splice junctions are supported by at least one non-suspect mRNA.</p><p>The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users, based on the type and quality of the alignments used to annotate the transcript.</p>TSL:1, |
| Ncoa1-207 | ENSMUST00000219373.1 | 781 | 154aa | ENSMUSP00000151608.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | - | A0A1W2P7D7 | 5' truncation in transcript evidence prevents annotation of the start of the CDS.CDS 5' incomplete, <p>TSL 2: A transcript where the best supporting mRNA is flagged as suspect or the support is from multiple ESTs</p><p>The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users, based on the type and quality of the alignments used to annotate the transcript.</p>TSL:2, |
| Ncoa1-206 | ENSMUST00000219275.1 | 745 | 99aa | ENSMUSP00000151904.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | - | A0A1W2P881 | 5' truncation in transcript evidence prevents annotation of the start of the CDS.CDS 5' incomplete, <p>TSL 3: A transcript where the only support is from a single EST</p><p>The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users, based on the type and quality of the alignments used to annotate the transcript.</p>TSL:3, |
| Ncoa1-208 | ENSMUST00000219715.1 | 542 | 54aa | ENSMUSP00000151302.1 | Gene/transcipt that contains an open reading frame (ORF).Protein coding | - | A0A1W2P6K7 | 3' truncation in transcript evidence prevents annotation of the end of the CDS.CDS 3' incomplete, <p>TSL 3: A transcript where the only support is from a single EST</p><p>The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users, based on the type and quality of the alignments used to annotate the transcript.</p>TSL:3, |
| Ncoa1-203 | ENSMUST00000217794.1 | 4917 | 1330aa | ENSMUSP00000151716.1 | Nonsense mediated decay | - | P70365 | <p>TSL 1: A transcript where all splice junctions are supported by at least one non-suspect mRNA.</p><p>The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users, based on the type and quality of the alignments used to annotate the transcript.</p>TSL:1, |
| Ncoa1-204 | ENSMUST00000217822.1 | 365 | No protein | - | An alternatively spliced transcript believed to contain intronic sequence relative to other, coding, transcripts of the same gene.Retained intron | - | - | <p>TSL 3: A transcript where the only support is from a single EST</p><p>The Transcript Support Level (TSL) is a method to highlight the well-supported and poorly-supported transcript models for users, based on the type and quality of the alignments used to annotate the transcript.</p>TSL:3, |
